ZNF750 Q32MQ0

锌指蛋白 750

功能描述

参与表皮分化的转录因子。为终末表皮分化所必需：位于p63/TP63下游并激活晚期表皮分化基因的表达。特异性结合KLF4的启动子并促进其表达。 {ECO:0000269|PubMed:22364861}。

组织特异性

Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.

亚细胞定位

Nucleus