ZNF652 Q9Y2D9

锌指蛋白 652

蛋白质信息 (UniProt)

锌指蛋白 652

Q9Y2D9

功能描述

DNA结合转录抑制因子，与CBFA2T2协同作用以抑制靶基因（如TCF12）的表达 (PubMed:16966434, PubMed:18456661, PubMed:21678463)。特异性结合DNA共有序列 5'-CGAAAGGGTTAAT-3' (PubMed:18456661, PubMed:21678463)。 {ECO:0000269|PubMed:16966434, ECO:0000269|PubMed:18456661, ECO:0000269|PubMed:21678463}。

组织特异性

Widely expressed with higher expression in breast, prostate, vulva and pancreas.

亚细胞定位

Nucleus

关键词

DNA-binding Metal-binding Nucleus Phosphoprotein Proteomics identification Reference proteome Repeat Repressor Transcription Transcription regulation

外部链接

UniProt: Q9Y2D9

NCBI Gene

GeneCards