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ZNF131 P52739

锌指蛋白 131

蛋白质信息 (UniProt)

锌指蛋白 131

P52739

功能描述

在发育和器官发生过程中以及在成体中枢神经系统功能中发挥作用 (By similarity)。可能作为ESR1/ER-alpha信号传导的抑制因子参与转录调控。{ECO:0000250, ECO:0000269|PubMed:18847501, ECO:0000269|PubMed:22467880}。

组织特异性

Predominant expression is found in different brain areas such as the occipital and temporal lobe, the nucleus caudatus, hippocampus, and the cerebellum as well as in testis and thymus.

亚细胞定位

Nucleus

关键词

Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Proteomics identification Reference proteome Repeat Repressor Transcription