锌指蛋白42同源物 (Zfp-42) (低表达蛋白1) (REX-1) (hREX-1) (锌指蛋白754)
锌指蛋白42同源物 (Zfp-42) (低表达蛋白1) (REX-1) (hREX-1) (锌指蛋白754)
Q96MM3功能描述
参与多能性获得过程中X染色体失活的重编程。TSIX高效延伸所必需，TSIX是XIST的反义非编码RNA。结合TSIX启动子内的DXPas34增强子。参与ES细胞自我更新（通过相似性）。{ECO:0000250}。
组织特异性
Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.
亚细胞定位
Nucleus
关键词