YY1相关蛋白1 (肝细胞癌易感蛋白) (肝细胞癌相关蛋白2)
YY1相关蛋白1 (肝细胞癌易感蛋白) (肝细胞癌相关蛋白2)
Q9H869功能描述
与INO80染色质重塑复合物结合，该复合物负责转录调控、DNA修复和复制 (PubMed:27939641)。增强YY1的转录激活 (PubMed:14744866)。在细胞周期调控中发挥作用 (PubMed:17541814, PubMed:27939641)。 {ECO:0000269|PubMed:14744866, ECO:0000269|PubMed:17541814, ECO:0000269|PubMed:27939641}。
组织特异性
Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
亚细胞定位
Cytoplasm
关键词