WNT7B P56706

Wnt-7b蛋白

功能描述

七次跨膜受体frizzled家族成员的配体，在经典Wnt/β-catenin信号通路中发挥作用 (PubMed:30026314)。胎盘发育过程中绒毛膜和尿囊正常融合所必需 (By similarity)。中枢神经系统 (CNS) 血管生成和血脑屏障调节所必需 (PubMed:30026314)。 {ECO:0000250|UniProtKB:P28047, ECO:0000269|PubMed:30026314}。

组织特异性

Moderately expressed in fetal brain, weakly expressed in fetal lung and kidney, and faintly expressed in adult brain, lung and prostate.

亚细胞定位

Secreted, extracellular space, extracellular matrix