WW结构域结合蛋白11 (WBP-11) (Npw38结合蛋白) (NpwBP) (SH3结构域结合蛋白SNP70) (与PQBP-1和PP1相互作用的剪接因子)
WW结构域结合蛋白11 (WBP-11) (Npw38结合蛋白) (NpwBP) (SH3结构域结合蛋白SNP70) (与PQBP-1和PP1相互作用的剪接因子)
Q9Y2W2功能描述
激活pre-mRNA剪接。可能抑制PP1磷酸酶活性。 {ECO:0000269|PubMed:10593949, ECO:0000269|PubMed:11375989, ECO:0000269|PubMed:14640981}.
组织特异性
Ubiquitous. Highly expressed in the heart, pancreas, kidney skeletal muscle, placenta and brain (at protein level). Weakly expressed in liver and lung.
亚细胞定位
Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
关键词