VPS37A Q8NEZ2

液泡蛋白分选相关蛋白37A (hVps37A) (ESCRT-I复合体亚基VPS37A) (肝细胞癌相关蛋白1)

功能描述

ESCRT-I复合物的组分，囊泡运输过程的调节因子。为将内吞泛素化货物分选进入多囊泡体所需。可能参与细胞生长和分化。{ECO:0000269|PubMed:15240819}。

组织特异性

Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.

亚细胞定位

Late endosome membrane; Peripheral membrane protein. Nucleus.