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VAV1 P15498

原癌基因 vav

蛋白质信息 (UniProt)

原癌基因 vav

P15498

功能描述

将酪氨酸激酶信号与Rho/Rac GTPases的激活偶联,从而导致细胞分化和/或增殖。

组织特异性

Widely expressed in hematopoietic cells but not in other cell types.

关键词

3D-structure Alternative splicing Guanine-nucleotide releasing factor Metal-binding Phosphoprotein Proteomics identification Proto-oncogene Reference proteome Repeat SH2 domain