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VASN Q6EMK4

血管生成素样蛋白 (Slit样蛋白2)

蛋白质信息 (UniProt)

血管生成素样蛋白 (Slit样蛋白2)

Q6EMK4

功能描述

可能作为TGF-beta信号传导的抑制剂。 {ECO:0000269|PubMed:15247411}。

组织特异性

Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.

亚细胞定位

Membrane

关键词

Disulfide bond EGF-like domain Glycoprotein Leucine-rich repeat Membrane Proteomics identification Reference proteome Repeat Secreted Signal