TXN2 Q99757

硫氧还蛋白，线粒体 (MTRX) (Mt-Trx) (硫氧还蛋白-2)

蛋白质信息 (UniProt)

硫氧还蛋白，线粒体 (MTRX) (Mt-Trx) (硫氧还蛋白-2)

Q99757

功能描述

对线粒体活性氧稳态、细胞凋亡调节和细胞存活的控制很重要 (PubMed:12032145, PubMed:12080052, PubMed:26626369)。参与各种氧化还原反应，包括通过其活性中心二硫醇可逆氧化为二硫化物来还原蛋白质二硫键 (By similarity)。 {ECO:0000250|UniProtKB:P97615, ECO:0000269|PubMed:12032145, ECO:0000269|PubMed:12080052, ECO:0000269|PubMed:26626369}。

组织特异性

Widely expressed in adult (at protein level) and fetal tissues.

亚细胞定位

Mitochondrion

关键词

3D-structure Acetylation Direct protein sequencing Disulfide bond Electron transport Mitochondrion Neurodegeneration Primary mitochondrial disease Proteomics identification Redox-active center

外部链接

UniProt: Q99757

NCBI Gene

GeneCards