Tau-微管激酶1 (EC 2.7.11.1) (脑源性Tau激酶)
Tau-微管激酶1 (EC 2.7.11.1) (脑源性Tau激酶)
Q5TCY1功能描述
丝氨酸/苏氨酸激酶，能够磷酸化TAU的丝氨酸、苏氨酸和酪氨酸残基。诱导TAU聚集。 {ECO:0000269|PubMed:16923168}。
组织特异性
Expressed in the brain, particularly in cortical and hippocampal neurons. Weakly expressed in spinal cord and testis. No expression in adipose tissue, bladder, cervix, colon, esophagus, heart, kidney, liver, lung, ovary, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus, thyroid or trachea.
亚细胞定位
Cytoplasm
关键词