转录调节因子1 (乳腺癌抗雌激素耐药蛋白2) (转录调节蛋白132) (锌指蛋白rapa) (锌指转录因子TReP-132)
转录调节因子1 (乳腺癌抗雌激素耐药蛋白2) (转录调节蛋白132) (锌指蛋白rapa) (锌指转录因子TReP-132)
Q96PN7功能描述
结合DNA并激活CYP11A1的转录。与CREBBP和EP300相互作用导致CYP11A1的协同转录激活。 {ECO:0000269|PubMed:11349124, ECO:0000269|PubMed:16371131}。
组织特异性
Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.
亚细胞定位
Nucleus
关键词