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TNNT2 P45379

心肌肌钙蛋白T (TnTc) (心肌肌钙蛋白T) (cTnT)

蛋白质信息 (UniProt)

心肌肌钙蛋白T (TnTc) (心肌肌钙蛋白T) (cTnT)

P45379

功能描述

Troponin T是troponin的tropomyosin结合亚基,troponin是细丝调节复合物,赋予横纹肌actomyosin ATPase活性钙敏感性。

组织特异性

Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.

关键词

3D-structure Acetylation Alternative splicing Cardiomyopathy Direct protein sequencing Disease variant Muscle protein Phosphoprotein Proteomics identification Reference proteome