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TMEM14A Q9Y6G1

跨膜蛋白14A

蛋白质信息 (UniProt)

跨膜蛋白14A

Q9Y6G1

功能描述

通过负向调控参与凋亡信号通路的线粒体外膜通透化来抑制细胞凋亡。 {ECO:0000269|PubMed:21723035}。

组织特异性

Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level).

亚细胞定位

Mitochondrion membrane

关键词

3D-structure Apoptosis Endoplasmic reticulum Membrane Mitochondrion Proteomics identification Reference proteome Transmembrane Transmembrane helix