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TLR10 Q9BXR5

Toll样受体10 (CD抗原CD290)

蛋白质信息 (UniProt)

Toll样受体10 (CD抗原CD290)

Q9BXR5

功能描述

参与针对微生物的先天免疫反应。通过MYD88和TRAF6发挥作用,导致NF-kappa-B激活、细胞因子分泌和炎症反应(By similarity)。 {ECO:0000250}。

组织特异性

Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

亚细胞定位

Membrane

关键词

3D-structure Glycoprotein Immunity Inflammatory response Innate immunity Leucine-rich repeat Membrane NAD Proteomics identification Receptor