紧密连接蛋白 2 (紧密连接蛋白 ZO-2) (闭锁小带蛋白 2) (闭锁小带蛋白 2)
紧密连接蛋白 2 (紧密连接蛋白 ZO-2) (闭锁小带蛋白 2) (闭锁小带蛋白 2)
Q9UDY2功能描述
在紧密连接和粘附连接中发挥作用 (By similarity)。作为RANKL诱导的破骨细胞分化的正调节因子，可能通过介导下游转录活性发挥作用 (By similarity)。 {ECO:0000250|UniProtKB:Q9Z0U1}。
组织特异性
This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues.
亚细胞定位
Cell junction, adherens junction
关键词