THAP5 Q7Z6K1

含THAP结构域蛋白5

蛋白质信息 (UniProt)

含THAP结构域蛋白5

Q7Z6K1

功能描述

具有序列特异性DNA结合活性，并可作为转录抑制因子发挥作用（体外）（PubMed:21110952）。可能是细胞周期调节因子：THAP5在人细胞系中过表达导致细胞周期阻滞于G2/M期（PubMed:19502560）。{ECO:0000269|PubMed:21110952, ECO:0000305|PubMed:19502560}。

组织特异性

Detected in heart (PubMed:19502560, PubMed:21195082). Detected in brain and muscle (at protein level) (PubMed:19502560). Highly expressed in the heart. Also found in brain and skeletal muscle (PubMed:19502560, PubMed:21195082).

亚细胞定位

Nucleus

关键词

Alternative splicing Cell cycle Coiled coil DNA-binding Metal-binding Nucleus Proteomics identification Reference proteome Repressor Transcription

外部链接

UniProt: Q7Z6K1

NCBI Gene

GeneCards