转录因子Dp家族成员3 (癌/睾丸抗原30) (CT30) (肝细胞癌相关抗原661)
转录因子Dp家族成员3 (癌/睾丸抗原30) (CT30) (肝细胞癌相关抗原661)
Q5H9I0功能描述
E2F介导的反式激活活性的竞争性抑制剂。阻碍E2F介导的细胞周期从G(1)期向S期进程。 {ECO:0000269|PubMed:16418725, ECO:0000269|PubMed:17062573, ECO:0000269|PubMed:20559320}.
组织特异性
Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.
亚细胞定位
Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.
关键词