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TAS2R3 Q9NYW6

味觉受体2型成员3 (T2R3)

蛋白质信息 (UniProt)

味觉受体2型成员3 (T2R3)

Q9NYW6

功能描述

与Gustducin偶联的受体,参与口腔和胃肠道中苦味化合物的感知。通过PLCB2和钙调节阳离子通道TRPM5发出信号。 {ECO:0000269|PubMed:10761934, ECO:0000269|PubMed:10761935}。

组织特异性

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.

亚细胞定位

Membrane; Multi-pass membrane protein.

关键词

G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Sensory transduction Taste Transducer Transmembrane Transmembrane helix