味觉受体2型成员3 (T2R3)
味觉受体2型成员3 (T2R3)
Q9NYW6功能描述
与Gustducin偶联的受体,参与口腔和胃肠道中苦味化合物的感知。通过PLCB2和钙调节阳离子通道TRPM5发出信号。 {ECO:0000269|PubMed:10761934, ECO:0000269|PubMed:10761935}。
组织特异性
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.
亚细胞定位
Membrane; Multi-pass membrane protein.
关键词