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SYP P08247

突触素 (主要突触囊泡蛋白 p38)

蛋白质信息 (UniProt)

突触素 (主要突触囊泡蛋白 p38)

P08247

功能描述

可能参与结构功能,如组织其他膜成分,或参与将囊泡靶向至细胞膜。参与短期和长期突触可塑性的调节 (By similarity)。 {ECO:0000250}。

组织特异性

Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578). Expressed in the putamen (at protein level) (PubMed:17296554).

亚细胞定位

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

关键词

Alternative splicing Calcium Cytoplasmic vesicle Disease variant Glycoprotein Intellectual disability Membrane Phosphoprotein Proteomics identification Reference proteome