突触塔布林 (高尔基定位突触亲和素相关蛋白) (突触融合蛋白-1结合蛋白)
突触塔布林 (高尔基定位突触亲和素相关蛋白) (突触融合蛋白-1结合蛋白)
Q9NX95功能描述
Kinesin马达-适配体复合物的一部分,该复合物对于活性区成分的顺行轴突运输至关重要,并在神经元发育过程中促进依赖于活性的突触前组装。 {ECO:0000250, ECO:0000269|PubMed:15459722}。
组织特异性
Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine.
亚细胞定位
[Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=Colocalizes with syntaxin vesicles along microtubules in neuronal processes.; SUBCELLULAR LOCATION: [Isoform 3]: Golgi apparatus membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform 4]: Golgi apparatus membrane; Single-pass membrane protein.; SUBCELLULAR LOCATION: [Isoform 5]: Golgi apparatus membrane; Single-pass membrane protein.
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