SUSD2 Q9UGT4

含Sushi结构域蛋白2

功能描述

可能是GPR15LG的细胞因子受体。可能是肿瘤抑制因子；与GPR15LG一起对结肠癌细胞具有生长抑制作用，包括G1细胞周期阻滞 (PubMed:25351403)。可能在乳腺肿瘤发生中发挥作用 (PubMed:23131994)。 {ECO:0000269|PubMed:23131994, ECO:0000269|PubMed:25351403}。

组织特异性

Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403).

亚细胞定位

Cell membrane