磺基转移酶 4A1 (ST4A1) (EC 2.8.2.-) (脑磺基转移酶样蛋白) (hBR-STL) (hBR-STL-1) (神经系统磺基转移酶) (NST)
磺基转移酶 4A1 (ST4A1) (EC 2.8.2.-) (脑磺基转移酶样蛋白) (hBR-STL) (hBR-STL-1) (神经系统磺基转移酶) (NST)
Q9BR01功能描述
非典型磺基转移酶家族成员，对3'-磷酸-5'-腺苷酰硫酸(PAPS)亲和力极低，对L-三碘甲状腺原氨酸、甲状腺素、雌酮、对硝基苯酚、2-萘胺和2-β-萘酚的催化活性极低。可能在CNS中药物和神经递质的代谢中发挥作用。 {ECO:0000269|PubMed:17425406}。
组织特异性
Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe, slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030).
亚细胞定位
Cytoplasm
关键词