SPINK9 Q5DT21

丝氨酸蛋白酶抑制剂Kazal型9 (淋巴上皮Kazal型相关抑制剂2)

功能描述

丝氨酸蛋白酶抑制剂，特异性抑制 KLK5。可能通过抑制 KLK5 参与皮肤脱屑过程的调节。 {ECO:0000269|PubMed:19190773, ECO:0000269|PubMed:19194479}。

组织特异性

Skin. Highly expressed at sites of hyperkeratosis. Also detected in thymus, tonsils, testis, pancreas, liver, placenta and brain. Expressed at stratum granulosum and stratum corneum at palmar and plantar sites (at protein level).

亚细胞定位

Secreted