含SAM pointed结构域Ets转录因子 (前列腺上皮特异性Ets转录因子) (前列腺特异性Ets) (前列腺来源Ets因子)
含SAM pointed结构域Ets转录因子 (前列腺上皮特异性Ets转录因子) (前列腺特异性Ets) (前列腺来源Ets因子)
O95238功能描述
可能作为前列腺特异性抗原(PSA)启动子的雄激素非依赖性反式激活因子发挥作用。结合5'-GGAT-3' DNA序列。可能在前列腺调节和/或前列腺癌发展中起作用。作为SERPINB5启动子的转录激活因子。 {ECO:0000269|PubMed:10625666}。
组织特异性
Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
亚细胞定位
Nucleus
关键词