SPATA9 Q9BWV2

精子发生相关蛋白9 (睾丸发育蛋白NYD-SP16)

功能描述

可能在睾丸发育/精子发生中发挥作用，并且可能是男性不育的一个重要因素。 {ECO:0000269|PubMed:12493713}。

组织特异性

Highly expressed in testes and pancreas. Low levels found in the heart, lungs, and brain. Very low expression detected in the placenta. No expression seen in skeletal muscle, liver, kidney, thymus, small intestine, colons, spleen, leukocytes, prostate gland, and ovary. In the adult testes, expression was about 6.44-fold higher than in the embryo testes. No expression in testes of patients with Sertoli-cell-only syndrome. In patients with arrest at spermatogonium and primary spermatocyte stages, no expression was detected. In patients with arrest at the spermatid stage, expression level was weak or absent. Variable expression was seen in patients with spermatogenic arrest.

亚细胞定位

Membrane