精子相关抗原1 (HSD-3.8) (不育相关精子蛋白Spag-1)
精子相关抗原1 (HSD-3.8) (不育相关精子蛋白Spag-1)
Q07617功能描述
可能在纤毛动力蛋白臂的细胞质组装中发挥作用 (By similarity)。可能在受精过程中发挥作用。结合GTP并具有GTP酶活性。 {ECO:0000250, ECO:0000269|PubMed:11517287, ECO:0000269|PubMed:1299558}。
组织特异性
Present in most tissues, including lung, with the strongest expression in brain, colon, kidney, and testis. In sperm and testis, detected in particular in pachytene primary spermatocytes. Up-regulated in pancreatic tumor tissues and not in normal pancreatic tissue.
亚细胞定位
Cytoplasm
关键词