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SPACA6 W5XKT8

精子顶体膜相关蛋白6 (BACHELOR样蛋白)

蛋白质信息 (UniProt)

精子顶体膜相关蛋白6 (BACHELOR样蛋白)

W5XKT8

功能描述

受精过程中精子与卵膜融合所需的精子蛋白 (By similarity)。可能调节精子表面蛋白 DCST2 的表达 (By similarity)。 {ECO:0000250|UniProtKB:A0A8M9PDM1, ECO:0000250|UniProtKB:E9Q8Q8}。

组织特异性

Detected at the sperm head, equatorial region, neck and midpiece (at protein level) (PubMed:32210282). Expressed in testis (PubMed:24275887).

亚细胞定位

Cytoplasmic vesicle, secretory vesicle, acrosome membrane

关键词

3D-structure Alternative splicing Cytoplasmic vesicle Disulfide bond Fertilization Glycoprotein Immunoglobulin domain Membrane Proteomics identification Reference proteome