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SOS1 Q07889

七无同源物1 (SOS-1)

蛋白质信息 (UniProt)

七无同源物1 (SOS-1)

Q07889

功能描述

促进Ras结合的GDP与GTP的交换 (PubMed:8493579)。可能通过促进Ras激活,调节EGF诱导的MAP kinase MAPK3/ERK1的磷酸化 (PubMed:17339331)。作为三聚体复合物的催化组分,通过促进Rac特异性鸟苷酸交换因子(GEF)活性,参与从Ras到Rac的信号转导 (By similarity)。 {ECO:0000250|UniProtKB:Q62245, ECO:0000269|PubMed:17339331, ECO:0000269|PubMed:8493579}。

组织特异性

Expressed in gingival tissues.

关键词

3D-structure Alternative splicing Disease variant Guanine-nucleotide releasing factor Phosphoprotein Proteomics identification Reference proteome