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SLC43A1 O75387

大中性氨基酸转运蛋白小亚基3 (L型氨基酸转运蛋白3) (前列腺癌过表达基因1蛋白) (溶质载体家族43成员1)

蛋白质信息 (UniProt)

大中性氨基酸转运蛋白小亚基3 (L型氨基酸转运蛋白3) (前列腺癌过表达基因1蛋白) (溶质载体家族43成员1)

O75387

功能描述

介导中性氨基酸(如L-亮氨酸、L-异亮氨酸、L-缬氨酸和L-苯丙氨酸)转运的单向转运蛋白 (PubMed:12930836)。该转运活性不依赖钠离子,呈电中性,并通过协助扩散进行介导 (PubMed:12930836)。 {ECO:0000269|PubMed:12930836}。

组织特异性

Ubiquitously expressed in fetus and adult (PubMed:9722952). Highest expression in adult pancreas, liver, skeletal muscle (PubMed:12930836, PubMed:9722952). In fetus, highest expression in liver and lower levels in kidney, and lung (PubMed:12930836). Exclusively expressed in the glomeruli along the glomerular capillary walls (PubMed:19443642).

亚细胞定位

Cell membrane

关键词

Alternative splicing Amino-acid transport Cell membrane Endoplasmic reticulum Glycoprotein Membrane Phosphoprotein Proteomics identification Reference proteome Transmembrane