佩德林 (不依赖钠的氯/碘转运蛋白) (溶质载体家族26成员4)
佩德林 (不依赖钠的氯/碘转运蛋白) (溶质载体家族26成员4)
O43511功能描述
氯离子和碘离子的非钠依赖性转运蛋白 (PubMed:10192399, PubMed:11932316, PubMed:12107249, PubMed:16684826, PubMed:24051746)。以1:1的化学计量介导电中性的氯离子-碳酸氢盐、氯离子-碘离子和氯离子-甲酸盐交换 (PubMed:10644529, PubMed:15155570, PubMed:24051746, PubMed:35601831)。介导电中性的碘离子-碳酸氢盐交换 (By similarity)。 {ECO:0000250|UniProtKB:Q9R155, ECO:0000269|PubMed:10192399, ECO:0000269|PubMed:10644529, ECO:0000269|PubMed:11932316, ECO:0000269|PubMed:12107249, ECO:0000269|PubMed:15155570, ECO:0000269|PubMed:16684826, ECO:0000269|PubMed:24051746, ECO:0000269|PubMed:35601831}。
组织特异性
Highly expressed in the kidney (at protein level) (PubMed:11274445). High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues (PubMed:9398842).
亚细胞定位
Cell membrane
关键词