SIPA1 Q96FS4

信号诱导增殖相关蛋白1 (Sipa-1) (GTP酶激活蛋白Spa-1) (p130 SPA-1)

功能描述

Rap1和Rap2的GTPase激活因子，在体外将它们转化为推测的无活性GDP结合状态 (PubMed:9346962)。影响细胞周期进程 (By similarity)。 {ECO:0000250|UniProtKB:P46062, ECO:0000269|PubMed:9346962}。

组织特异性

Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.

亚细胞定位

Nucleus