核苷酸交换因子SIL1 (BiP相关蛋白) (BAP)
核苷酸交换因子SIL1 (BiP相关蛋白) (BAP)
Q9H173功能描述
内质网(ER)中的protein转运和折叠所必需。作为ER腔chaperone HSPA5的nucleotide exchange factor发挥作用。 {ECO:0000269|PubMed:12356756}。
组织特异性
Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain.
亚细胞定位
Endoplasmic reticulum lumen
关键词