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SIGLEC9 Q9Y336

唾液酸结合Ig样凝集素9 (Siglec-9) (CDw329) (蛋白 FOAP-9) (CD抗原 CD329)

蛋白质信息 (UniProt)

唾液酸结合Ig样凝集素9 (Siglec-9) (CDw329) (蛋白 FOAP-9) (CD抗原 CD329)

Q9Y336

功能描述

功能:推定的粘附分子,介导依赖唾液酸的细胞结合。优先结合α-2,3-或α-2,6-连接的唾液酸。唾液酸识别位点可能被与同一细胞表面唾液酸的顺式相互作用所遮蔽。

组织特异性

Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon.

亚细胞定位

Membrane; Single-pass type I membrane protein.

关键词

Alternative splicing Cell adhesion Disulfide bond Glycoprotein Immunoglobulin domain Lectin Membrane Proteomics identification Reference proteome Repeat