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SHROOM4 Q9ULL8

Shroom4蛋白 (顶端蛋白第二同源物)

蛋白质信息 (UniProt)

Shroom4蛋白 (顶端蛋白第二同源物)

Q9ULL8

功能描述

可能的细胞骨架结构调节因子,在发育中起重要作用。可能通过调节肌球蛋白II的空间分布来调控细胞和细胞骨架结构(通过相似性)。{ECO:0000250, ECO:0000269|PubMed:16684770}。

组织特异性

Expressed in all fetal and adult tissues investigated. Expressed in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. In brain regions detected in cerebellum, cerebral cortex, medulla, spinal cord, occipital pole, frontal lobe, temporal lobe and putamen. The expression is strongest in the medulla and weakest in the cerebral cortex.

亚细胞定位

Cytoplasm, cytoskeleton

关键词

3D-structure Actin-binding Alternative splicing Chromosomal rearrangement Coiled coil Cytoplasm Cytoskeleton Developmental protein Intellectual disability Phosphoprotein