SHC3 Q92529

SHC转化蛋白3 (神经元Shc) (N-Shc) (Rai蛋白) (SHC转化蛋白C) (含Src同源2结构域转化蛋白C3) (SH2结构域蛋白C3)

功能描述

信号接头蛋白，将激活的生长因子受体偶联到神经元的信号通路中。参与皮层神经元中神经营养蛋白激活的Trk受体的信号转导通路。

组织特异性

Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.