SERPING1 P05155

血浆蛋白酶C1抑制剂 (C1 Inh) (C1Inh) (C1酯酶抑制剂) (C1抑制因子) (Serpin G1)

蛋白质信息 (UniProt)

血浆蛋白酶C1抑制剂 (C1 Inh) (C1Inh) (C1酯酶抑制剂) (C1抑制因子) (Serpin G1)

P05155

功能描述

丝氨酸蛋白酶抑制剂，作为经典补体途径的调节因子 (PubMed:10946292, PubMed:11527969, PubMed:3458172, PubMed:6416294)。与C1r或C1s蛋白酶形成无蛋白水解活性的化学计量复合物 (PubMed:10946292, PubMed:3458172, PubMed:6416294)。可能还调节血液凝固、纤维蛋白溶解和激肽的生成 (PubMed:8495195)。FXIIa的极有效抑制剂。抑制糜蛋白酶和激肽释放酶 (PubMed:8495195)。 {ECO:0000269|PubMed:10946292, ECO:0000269|PubMed:11527969, ECO:0000269|PubMed:3458172, ECO:0000269|PubMed:6416294, ECO:0000269|PubMed:8495195}。

亚细胞定位

Secreted

关键词

3D-structure Alternative splicing Blood coagulation Direct protein sequencing Disease variant Disulfide bond Fibrinolysis Glycoprotein Hemostasis Protease inhibitor

外部链接

UniProt: P05155

NCBI Gene

GeneCards