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SCUBE1 Q8IWY4

信号肽、CUB和EGF样结构域包含蛋白1

蛋白质信息 (UniProt)

信号肽、CUB和EGF样结构域包含蛋白1

Q8IWY4

功能描述

可能作为粘附分子发挥作用,其基质结合片段和可溶性片段可能在血管生物学中发挥关键作用。 {ECO:0000269|PubMed:16753137}。

组织特异性

Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.

亚细胞定位

Secreted

关键词

Calcium Cell membrane Disulfide bond EGF-like domain Glycoprotein Membrane Proteomics identification Reference proteome Repeat Secreted