信号肽、CUB和EGF样结构域包含蛋白1
信号肽、CUB和EGF样结构域包含蛋白1
Q8IWY4功能描述
可能作为粘附分子发挥作用,其基质结合片段和可溶性片段可能在血管生物学中发挥关键作用。 {ECO:0000269|PubMed:16753137}。
组织特异性
Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques.
亚细胞定位
Secreted
关键词