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SAMD9L Q8IVG5

含无菌α基序结构域蛋白9样 (含SAM结构域蛋白9样)

蛋白质信息 (UniProt)

含无菌α基序结构域蛋白9样 (含SAM结构域蛋白9样)

Q8IVG5

功能描述

可能参与内体融合。通过生长因子受体的内化介导生长因子信号的下调。 {ECO:0000250|UniProtKB:Q69Z37}。

组织特异性

Widely expressed in adult and fetal tissues. Expressed in the cerebellum (PubMed:35310830). Variable expression in tumors. Down-regulated in breast cancer.

亚细胞定位

Early endosome

关键词

Alternative splicing Disease variant Endosome Mitochondrion Neurodegeneration Proteomics identification Reference proteome Spinocerebellar ataxia