RTKN Q9BST9

罗特金蛋白

功能描述

介导Rho信号传导以激活NF-kappa-B，并可能在胃肿瘤发生过程中赋予细胞增加的凋亡抗性。可能在septin结构的组织中发挥新作用。 {ECO:0000269|PubMed:10940294, ECO:0000269|PubMed:15480428, ECO:0000269|PubMed:16007136}.

组织特异性

Highly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines.