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RRAS2 P62070

Ras相关蛋白R-Ras2 (EC 3.6.5.2) (Ras样蛋白TC21) (畸胎癌癌基因)

蛋白质信息 (UniProt)

Ras相关蛋白R-Ras2 (EC 3.6.5.2) (Ras样蛋白TC21) (畸胎癌癌基因)

P62070

功能描述

具有GTPase活性的GTP结合蛋白,参与MAPK信号通路的调节,从而控制多种细胞过程 (PubMed:31130282, PubMed:31130285, PubMed:39809765)。调节颅面发育 (PubMed:31130282, PubMed:31130285)。 {ECO:0000269|PubMed:31130282, ECO:0000269|PubMed:31130285, ECO:0000269|PubMed:39809765}。

组织特异性

Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.

亚细胞定位

Cell membrane

关键词

3D-structure Acetylation Alternative splicing Cell membrane Disease variant Golgi apparatus GTP-binding Hydrolase Lipoprotein Membrane