RHOXF1 Q8NHV9

Rhox同源盒家族成员1 (卵巢、睾丸和附睾表达基因蛋白) (配对样同源盒蛋白PEPP-1)

功能描述

转录因子，可能参与生殖过程。调节编码参与精子发生相关过程的蛋白质的目标基因的表达。 {ECO:0000269|PubMed:28171660}。

组织特异性

Ovary, testis and epididymis. Also detected in the prostate and the mammary gland. Expressed in many tumor cell lines derived from acute lymphocytic leukemia, prostate, endometrial adenocarcinoma, melanoma, bladder carcinoma, colon carcinoma, erythroleukemia and breast carcinoma. Not expressed in placenta. In testis, mainly expressed in germ cells, but also detected in somatic cells such as Sertoli cells, Leydig cells and peritubular cells (PubMed:28171660).

亚细胞定位

Nucleus