RHOT2 Q8IXI1

线粒体Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras同源基因家族成员T2)

蛋白质信息 (UniProt)

线粒体Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras同源基因家族成员T2)

Q8IXI1

功能描述

非典型线粒体核苷三磷酸酶 (NTPase)，参与线粒体运输 (PubMed:16630562, PubMed:22396657, PubMed:30513825)。可能参与控制线粒体的顺向运输及其亚细胞分布 (PubMed:22396657)。能够水解GTP (By similarity)。能够水解ATP和UTP (PubMed:30513825)。 {ECO:0000250|UniProtKB:Q8IXI2, ECO:0000269|PubMed:16630562, ECO:0000269|PubMed:22396657, ECO:0000269|PubMed:30513825}。

组织特异性

Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.

亚细胞定位

Mitochondrion outer membrane

关键词

3D-structure Alternative splicing Calcium GTP-binding Hydrolase Isopeptide bond Magnesium Membrane Metal-binding Mitochondrion

外部链接

UniProt: Q8IXI1

NCBI Gene

GeneCards