G蛋白信号调节因子4 (RGP4) (RGS4)
G蛋白信号调节因子4 (RGP4) (RGS4)
P49798功能描述
通过增加G蛋白α亚基的GTPase活性从而使其转变为非活性的GDP结合形式，进而抑制信号转导。对G(z)-alpha的活性受G蛋白磷酸化的抑制。对G(z)-alpha和G(i)-alpha-1的活性受G蛋白棕榈酰化的抑制。
组织特异性
Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum.
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