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RFX4 Q33E94

转录因子RFX4 (调节因子X 4) (睾丸发育蛋白NYD-SP10)

蛋白质信息 (UniProt)

转录因子RFX4 (调节因子X 4) (睾丸发育蛋白NYD-SP10)

Q33E94

功能描述

在早期大脑发育中发挥作用的转录因子。可能通过与X-box直接相互作用来激活转录。可能在脑发育过程中通过X-box激活CX3CL1启动子的转录。胚胎发生过程中神经管纤毛发生可能需要此蛋白(By similarity)。 {ECO:0000250|UniProtKB:A0A1L8GWK2, ECO:0000250|UniProtKB:Q7TNK1}。

组织特异性

Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spermatozoa than in fetal testes. Isoform 4: Testis-specific.

亚细胞定位

Nucleus

关键词

Activator Alternative splicing DNA-binding Nucleus Proteomics identification Reference proteome Transcription Transcription regulation