REM1 O75628

GTP结合蛋白REM 1 (GTP酶调节内皮细胞发芽) (Rad和Gem样GTP结合蛋白1)

功能描述

促进内皮细胞出芽和肌动蛋白细胞骨架重组。可能参与血管生成。可能在Ca(2+)信号传导中发挥作用。

组织特异性

Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate.