再生胰岛衍生蛋白 4 (REG-4) (胃肠道分泌蛋白) (REG样蛋白) (再生胰岛衍生蛋白 IV) (Reg IV)
再生胰岛衍生蛋白 4 (REG-4) (胃肠道分泌蛋白) (REG样蛋白) (再生胰岛衍生蛋白 IV) (Reg IV)
Q9BYZ8功能描述
一种不依赖钙离子的凝集素，显示甘露糖结合特异性，并能在酸性环境中保持碳水化合物识别活性。可能参与胃肠道上皮的炎症和化生反应。 {ECO:0000269|PubMed:12819006, ECO:0000269|PubMed:20692269}。
组织特异性
Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
亚细胞定位
Secreted
关键词