RASL11A Q6T310

Ras样蛋白家族成员11A (EC 3.6.5.2)

功能描述

rDNA转录调节因子。与UBF/UBTF协同作用，正调控RNA聚合酶I转录（通过相似性）。{ECO:0000250}。

组织特异性

Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.

亚细胞定位

Nucleus, nucleolus