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PXK Q7Z7A4

含PX域蛋白激酶样蛋白 (Na,K-ATPase调节因子) (MONaKA)

蛋白质信息 (UniProt)

含PX域蛋白激酶样蛋白 (Na,K-ATPase调节因子) (MONaKA)

Q7Z7A4

功能描述

结合并调节脑Na,K-ATPase亚基ATP1B1和ATP1B3,从而可能参与电兴奋性和突触传递的调节。可能不显示激酶活性。 {ECO:0000250|UniProtKB:Q8BX57, ECO:0000303|PubMed:16142408}。

组织特异性

Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.

亚细胞定位

Cytoplasm

关键词

Actin-binding Alternative splicing Cell membrane Cytoplasm Membrane Proteomics identification Reference proteome